August 2004, BioGene/SoftGenetics
Enhanced Alignment & Indel Detection
SoftGenetics Teams with BioGene in the UK
We would like to introduce you to two exciting events,
both recently done to enhance our services and products
for the United Kingdom research community!
1. Enhanced Indel Detection:
Perhaps some of you were present at a recent discussion
of DNA variant software packages where it was indicated
that although Mutation Surveyor is an excellent program,
it had a shortcoming relating to the detection of short
Indels. We are pleased to inform you that our development
team, which had been working on this particular issue for
some time, has improved the software so that this is now
possible.
We are also pleased to inform you that version 2.4 of Mutation
Surveyor (to be released shortly) has a second alignment
algorithm that, when combined with our robust linear alignment
algorithm, has proven to be effective in detecting 1bp Indels,
as well as having the capability to align sequences containing
up to 10% variants from the reference:
|
Figure 1
Detection of 1bp indel |
|
Figure 2.
Mutation Surveyor’s new alignment engine will
align traces containing up 10% variation vs. reference
trace |
2. BioGene Appointed as UK Representative:
We are pleased to announce the appointment of BioGene as
the United Kingdom representatives for SoftGenetics.
We are confident that our new business agreement will provide
UK researchers with the strongest possible partnership of
product and technical support. Please contact BioGene with
questions or to receive a 30 day trial version of SoftGenetics’
Variant Analysis Software and/or our new GeneMarker AFLP/Genotyping
software.
SoftGenetics products are available now!
SoftGenetics
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