Introducing GeneMarker for MS-MLPA.
DNA methylation is the addition of a methyl
group to a piece of DNA, specifically to cytosines located
in CG dinucleotide repeat regions. Regions of the genome
containing a high frequency of these dinucleotides are referred
to as CpG islands (1) and are often located in the promoter
region of genes. Virtually all vertebrate animals have methylation
sites in their genome. In humans, approximately 1% of DNA
bases undergo DNA methylation
GeneMarker DNA analysis software has been
successfully paired with the Multiplex Ligation-dependent
Probe Amplification (MLPA®) technique for detecting
genetic deletions and duplications in various diseases including
cancer. For more details, download the PDF by clicking on
the link below.
For more details, download the 
(139 Kb) 