SENECA VALLEY VIRUS (SVV)
An SVV assay was developed to demonstrate that the CENOS Xtraction Free reagents could be used to rapidly deploy new assays in response to future emerging pathogens. Three tiled primers and two probes were tested using a dilution of SVV RNA extracted from a virus isolate. All primer combinations detected the SVV genomic RNA.
DIRECT FROM NASAL SWAB TESTING, NO EXTRACTION. ALL GENOTYPES COVERED.
We are developing an SVV assay that will detect all known genotypes directly from crude samples without extraction, such as nasal swabs and oral fluids.
- Sample type: nasal swabs and oral fluids
- Input: 16% v/v, no prep required
- LOD: predicted <1,000 virions/ml
- Time to result: ~30 minutes
- Cross-reactivity: non to any known veterinary pathogens
Use in outbreak regions for detection of symptomatic SVV infections, at borders and for surveillance and containment.
Performance data generated through an Innovate UK funded research project, involving The Pirbright Institute, demonstrate the rapid molecular detection capability of the CENOS platform under defined study conditions. The participating institutions do not endorse the product.